"Mental health research has lagged behind because we don't know what is happening biologically. Lucy Parsons. The researchers have also found preliminary evidence that the level of the protein is linked to cognitive performance in people with schizophrenia. "We believe this has direct implications for the treatment of patients," said senior author Consuelo Walss-Bass, Ph.D., professor in the Louis A. Faillace, MD, Department of Psychiatry and Behavioral Sciences at McGovern Medical School at UTHealth. Risk of withdrawal of consent for treatment with long-acting injectable versus oral antipsychotics: A meta-analysis of randomized controlled trials Available online 9 December 2020 The team scanned 18 adults with schizophrenia and compared them with 18 people without the condition. Among the differentially expressed genes along the pathway was one called serum-glucocorticoid kinase 1 (SGK1), an inhibitor of GSK3 beta, which has been associated with schizophrenia. This may be done to help rule out other problems that could be causing symptoms and to check for any related complications. Schizophrenia is a serious and chronic mental illness that impairs a person's thoughts and behavior, and if untreated, can include psychosis. Review Article. Schizophrenia has a lifetime prevalence of about 1% 4 and accounts for a huge health care burden, with annual associated costs in the United States estimated to be more than $150 billion. The study, published in Nature Communications, focused on measuring a protein found in synapses called SV2A, which has been shown to be a good marker of the overall density of connections in the brain. October 23, 2020. The loss of connections between brain cells could be responsible for an array of symptoms in people with schizophrenia. This could help pinpoint who may respond better to treatments.". Diagnosis of schizophrenia involves ruling out other mental health disorders and determining that symptoms are not due to substance abuse, medication or a medical condition. Your opinions are important to us. Daily science news on research developments and the latest scientific innovations, The latest engineering, electronics and technology advances, The most comprehensive sci-tech news coverage on the web. Recent Schizophrenia Research Articles Recently published articles from Schizophrenia Research. “But the debilitating cognitive symptoms, such as loss of abilities to plan and remember, often cause much more long-term disability and there’s no treatment for them at the moment.”. Prof Oliver Howes from the MRC London Institute of Medical Sciences, Imperial College London and King’s College London, who led the study, said: “Our current treatments for schizophrenia target only one aspect of the disease: the psychotic symptoms. 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